A. Diagnosis

A. Functional Zonation

B. Steroidogenic Pathways

A. Role of ACTH

1. Diurnal Rhythm of ACTH Release

2. Regulation of ACTH Release by Stress

B. Adrenal Steroid Hormones in Blood

C. Metabolism and Excretion of Adrenocortical Hormones

D. Regulation of Glucocorticoid Secretion

E. Biological Actions of Glucocorticoids

1. Intermediary Metabolism

2. Carbohydrate Metabolism

3. Protein Metabolism

4. Fat Metabolism

5. Circulatory Actions

6. Inflammatory and Immune Responses

7. Cortisol Action in Inflammation

8. CNS Effects

9. Developmental Effects

10. Features of Cortisol Deficiency

11. Features of Cortisol Excess

G. Regulation of Mineralocorticoid Secretion

1. Minor Regulators of Aldosterone Secretion

2. Aldosterone Action

3. Aldosterone Escape

4. Extrarenal Effects of Aldosterone

H. Androgen Secretion by the Adrenal Cortex

I. Steroidogenesis

1. Basic Steroidogenic Pathway

2. Some Rules of Nomenclature for Steroids

3. Steroid Hormone Biosynthesis

4. Pregnenolone: The Common Precursor for Steroid Hormones

5. Physiologically Important Adrenocortical Hormones: the Twenty-one Carbon Series

6. Physiologically Important Adrenocortical Hormones: the Nineteen Carbon Series

7. Physiologically Important Adrenocortical Hormones: the Eighteen Carbon Series

J. Congenital Adrenal Hyperplasia

1. Cholesterol Side-Chain Cleavage

2. 3-Hydrosteroid Dehydrogenase

3. 17-Hydroxylase

4. 21-Hydroxylase

5. 11-Hydroxylase

K. Adrenal Medulla: Introduction

1. Biosynthesis of the Catecholamines

2. Mechanism of Catecholamine Action

3. Storage and Release of Epinephrine

4. Metabolism of Catecholamines

5. Physiological Actions of Medullary Hormones

6. Regulation of Adrenal Medullary Function